首页> 外国专利> Convalescence allergy test or convalescence inflammation test

Convalescence allergy test or convalescence inflammation test

机译:恢复期过敏测试或恢复期炎症测试

摘要

(57) Abstract The possibility the child losing the allergy and the especially food allergy, by comparison with the IgE antibody of higher-order structural epitopu and immunity reactivity concerning the IgE antibody of direct condition epitopu and immunity reactivity it can estimate by the screening doing. The child is decided, first, the screening being done making use of standard technology, that whether some antigen it is allergy characteristic vis-a-vis the child. Next, as for the immunoglobulin in the sample of patient origin, the antigen and the rearrangement antigen which were refined from nature, restoration and to alkyl the synthetic peptide of the amino acid with 4 and 40 (as for these, it can characterize the proteolysis fragment, or length of the antigen and this antigen which are converted for quick and the accurate screening it can be fixed) making use of each of them. The protein or peptide being able to react the antibody of patient origin, it is decided whether some peptide it is connected by this antibody. Next, these antibodies, being characterized, are decided epitopu which these antibodies connect is direct condition whether, or whether it is higher-order structure. The patient who possesses the antibody which reacts with higher-order structural epitopu mainly, typically, loses the allergy. It can estimate the convalescence of inflammation characteristic obstacle of specification making use of the similar method regarding the appraisal of the IgG antibody.
机译:(57)<摘要>与直接结构性表位的IgE抗体和免疫反应性相关的高阶结构表位的IgE抗体和免疫反应性相比,儿童可能失去过敏,尤其是食物过敏的可能性,可以通过筛选做。首先,确定儿童是否使用标准技术进行筛查,以确定其对儿童是否具有某种抗原过敏性特征。接下来,对于患者来源的样品中的免疫球蛋白,从自然界中精制的抗原和重排抗原,通过将氨基酸的合成肽还原成4和40进行烷基化(这些可以表征蛋白水解作用)。片段或抗原和该抗原的长度,可以对其进行快速转换并进行准确的筛选,然后对其进行固定)。能与患者来源的抗体反应的蛋白质或肽,决定它是否被该抗体连接某些肽。接下来,表征这些抗体,决定这些抗体连接的表位是直接条件还是是否为高阶结构。拥有主要与高级结构表位反应的抗体的患者通常会失去过敏。关于IgG抗体的评价,可以使用类似的方法来估计规格的炎症特征障碍的恢复。

著录项

  • 公开/公告号JP2002502039A

    专利类型

  • 公开/公告日2002-01-22

    原文格式PDF

  • 申请/专利权人 サンプソン ヒュー エイ.;

    申请/专利号JP20000529614

  • 发明设计人 サンプソン ヒュー エイ.;

    申请日1999-01-28

  • 分类号G01N33/68;G01N33/15;G01N33/50;G01N33/53;

  • 国家 JP

  • 入库时间 2022-08-22 01:02:32

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