首页> 外国专利> Method for assessing the risk of peptic ulcer, comprising the steps of determining quantitatively the concentrations of pepsinogen i (pgi) and gastrin-17 in a serum sample

Method for assessing the risk of peptic ulcer, comprising the steps of determining quantitatively the concentrations of pepsinogen i (pgi) and gastrin-17 in a serum sample

机译:评估消化性溃疡风险的方法,包括定量测定血清样品中胃蛋白酶原i(pgi)和胃泌素17浓度的步骤

摘要

The present invention concerns a method for assessing the risk of peptic ulcer by determining the presence and topographic phenotype of gastritis in an individual, by determining quantitatively the pepsinogen I and gastin-17 concentrations in a serum sample from the said individual, selecting a method-specific reference value and cut-off value for respective analyte, assessing the topography and phenotype of gastritis based on a comparison of the pepsinogen I and gastrin-17 concentrations so determined with their respective method-specific reference and cut-off values, and correlating the so assessed gastritis phenotype with the risk for peptic ulcer. Preferably also Helicobacter antibodies are determined in the sample.
机译:本发明涉及一种通过确定个体中胃炎的存在和地形表型,通过定量确定来自所述个体的血清样品中的胃蛋白酶原I和胃泌素-17的浓度,评估方法来评估消化性溃疡风险的方法,相应分析物的特定参考值和临界值,根据胃蛋白酶原I和胃泌素17浓度与各自方法特定的参考值和临界值的比较来评估胃炎的形貌和表型,并将其关联因此评估胃炎表型与消化性溃疡的风险。优选地,还确定样品中的幽门螺杆菌抗体。

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