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DNA encoding proteins of Kaposi's sarcoma associated herpesvirus

机译:卡波济氏肉瘤相关疱疹病毒蛋白质的DNA编码

摘要

The present invention is directed to isolated nucleic acid molecules encoding proteins of Kaposi's sarcoma associated herpesvirus, including an antigenic receptor protein, a G protein coupled receptor, and a cyclin protein. Expression vectors and host cells comprising the nucleic acid molecules are also provided, as well as methods for increasing or decreasing the expression of the KSHV proteins in host cells. DNA oligomers and antibodies specific for the KSHV proteins are provided, each of which can be used to detect the KSHV proteins in a sample. Isolated KSHV proteins are also provided.
机译:本发明涉及编码卡波西氏肉瘤相关疱疹病毒蛋白的分离的核酸分子,包括抗原受体蛋白,G蛋白偶联受体和细胞周期蛋白。还提供了表达载体和包含核酸分子的宿主细胞,以及增加或减少KSHV蛋白在宿主细胞中表达的方法。提供了对KSHV蛋白特异的DNA寡聚体和抗体,每种寡核苷酸和抗体均可用于检测样品中的KSHV蛋白。还提供了分离的KSHV蛋白。

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