首页> 外国专利> COSMETIC OR PHARMACEUTICAL COMPOSITION HAVING PROTECYIVE EFFECTS OF GREEN TEA POLYPHENOLS

COSMETIC OR PHARMACEUTICAL COMPOSITION HAVING PROTECYIVE EFFECTS OF GREEN TEA POLYPHENOLS

机译:具有绿茶多酚保护作用的化妆品或药物组合物

摘要

PURPOSE: A cosmetic composition showing inhibition effect on collagenase formation by containing green tea polyphenol is provided, which shows excellent inhibition effect on collagen degradation. CONSTITUTION: A process for the preparation of cosmetic composition showing inhibition effect on collagenase formation comprises the steps of: adding green tea(Thea sinensis L.) to 95% ethanol, steeping for 5days, and filtering; separating organic solvent layer by using distilled water/ethyl acetate(1:1) solution; purifying 99% of (-)-epicatechin(EC), (-)-epigallocatechin(EGC), (-)-epicatechin 3-gallate(ECG), and epigallocatechin 3-0-gallate(EGCG) by separating with high performance liquid chromatography, and producing the green tea polyphenol (GTP). The cosmetic composition contains 0.00000001-30%(w/v) of GTP, desirably 0.00001-6%(w/v), as the weight after drying.
机译:用途:提供了一种化妆品组合物,其通过包含绿茶多酚显示出对胶原酶形成的抑制作用,该组合物显示出对胶原蛋白降解的优异抑制作用。组成:一种具有抑制胶原酶形成作用的化妆品组合物的制备方法,包括以下步骤:将绿茶(Thea sinensis L.)加入95%的乙醇中,浸泡5天,然后过滤;用蒸馏水/乙酸乙酯(1:1)溶液分离有机溶剂层;通过与高效液相色谱分离纯化99%的(-)-表儿茶素(EC),(-)-表儿茶素(EGC),(-)-表儿茶素3-没食子酸酯(ECG)和表没食子儿茶素3-0-没食子酸酯(EGCG)色谱,并生产绿茶多酚(GTP)。该化妆品组合物包含0.00000001-30%(w / v)的GTP,理想地为0.00001-6%(w / v),作为干燥后的重量。

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