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Retinoic Brass Tomato Proteins and Transcription Factors Retrieval of active regulators of transcription factors ETS1 or ETS2, including ETS1 or ETS2
Retinoic Brass Tomato Proteins and Transcription Factors Retrieval of active regulators of transcription factors ETS1 or ETS2, including ETS1 or ETS2
The present invention relates to a reagent for detecting an activity regulator of a retinobrassoma (Rb) protein and a transcription factor ets1 or ets2 containing the transcription factor ets1 or ets2, and a method of using the same, and specifically relates to a method for binding to the amino terminal of ets1 or ets2 The present invention relates to a reagent for regulating the activity of a transcription factor ets1 or ets2 comprising a carboxy terminus of Rb and ets1 or ets2 that inhibits the expression inducing activity of ets1 or ets2 and a method for using the same, Can be used as a therapeutic agent for pathological phenomena, for example, rheumatism and cancer cell metastasis, which are caused by an increase in gene expression depending on the factor ets1 or ets2.
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