首页> 外国专利> Retinoic Brass Tomato Proteins and Transcription Factors Retrieval of active regulators of transcription factors ETS1 or ETS2, including ETS1 or ETS2

Retinoic Brass Tomato Proteins and Transcription Factors Retrieval of active regulators of transcription factors ETS1 or ETS2, including ETS1 or ETS2

机译:维甲酸黄铜番茄蛋白和转录因子检索转录因子ETS1或ETS2(包括ETS1或ETS2)的活性调节剂

摘要

The present invention relates to a reagent for detecting an activity regulator of a retinobrassoma (Rb) protein and a transcription factor ets1 or ets2 containing the transcription factor ets1 or ets2, and a method of using the same, and specifically relates to a method for binding to the amino terminal of ets1 or ets2 The present invention relates to a reagent for regulating the activity of a transcription factor ets1 or ets2 comprising a carboxy terminus of Rb and ets1 or ets2 that inhibits the expression inducing activity of ets1 or ets2 and a method for using the same, Can be used as a therapeutic agent for pathological phenomena, for example, rheumatism and cancer cell metastasis, which are caused by an increase in gene expression depending on the factor ets1 or ets2.
机译:本发明涉及一种用于检测视网膜小管瘤(Rb)蛋白和含有转录因子ets1或ets2的转录因子ets1或ets2的活性调节剂的试剂,及其使用方法,特别涉及结合方法本发明涉及一种用于调节转录因子ets1或ets2的活性的试剂,该试剂包含Rb和ets1或ets2的羧基末端,抑制了ets1或ets2的表达诱导活性。使用它们,可以用作治疗风湿病和癌细胞转移的病理现象的治疗剂,风湿病和癌细胞转移是由基因表达增加所引起的,而基因表达取决于因子ets1或ets2。

著录项

  • 公开/公告号KR19990085356A

    专利类型

  • 公开/公告日1999-12-06

    原文格式PDF

  • 申请/专利权人 성재갑;

    申请/专利号KR19980017730

  • 发明设计人 양범석;김동명;손호선;

    申请日1998-05-16

  • 分类号C12Q1/28;

  • 国家 KR

  • 入库时间 2022-08-22 01:46:28

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