首页> 外国专利> H- AND L-CHAINS OF MONOCLONAL ANTIBODY PM-1 (MONAT) TO HUMAN IL-6R RECEPTOR AND THEIR V-REGION, MODIFIED MONAT, ITS H- AND L-CHAINS AND THEIR V-REGIONS, CDR-SEQUENCE, DNA-SEQUENCE

H- AND L-CHAINS OF MONOCLONAL ANTIBODY PM-1 (MONAT) TO HUMAN IL-6R RECEPTOR AND THEIR V-REGION, MODIFIED MONAT, ITS H- AND L-CHAINS AND THEIR V-REGIONS, CDR-SEQUENCE, DNA-SEQUENCE

机译：单克隆抗体PM-1（MONAT）对人IL-6R受体的H链和L链及其V区，修饰的MONAT，其H链和L链及其V区，CDR序列，DNA序列

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FIELD: biotechnology, immunology. SUBSTANCE: invention relates to the V-region of L-chain of murine monoclonal antibodies to human IL-6R and H-chain of V-region of murine monoclonal antibodies to human IL-6R. Also, modified antibodies to human IL-6R, DNA-sequence encoding the above indicated antibodies or their fragments are given. Antibodies to human IL-6R receptors can be used as a therapeutic agent for treatment of patients with myeloma. EFFECT: antibodies as the medicinal preparation. 24 cl, 24 dwg, 9 tbl, 17 ex

机译：领域：生物技术，免疫学。本发明涉及抗人IL-6R的鼠单克隆抗体的L链的V区和抗人IL-6R的鼠单克隆抗体的V区的H链。另外，给出了针对人IL-6R的修饰抗体，编码上述抗体或其片段的DNA序列。人IL-6R受体的抗体可用作治疗骨髓瘤患者的治疗剂。功效：抗体作为药物制剂。 24 cl，24 dwg，9 tbl，17 ex

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公开/公告号RU2139351C1

专利类型
公开/公告日1999-10-10

原文格式PDF
申请/专利权人 CHUGAI SEJJAKU KABUSIKI KAJSJA (JP);
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申请/专利号RU19930055358
发明设计人 MASAJUKI TSUTIJA (JP);KOKH SATO (JP);MEHRI MARGARET BENDIG (GB);STIVEN TARRAN DZHONS (GB);ZHOZE UILJAM SALDANKHA (GB);
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申请日1992-04-24
分类号C12P21/08;C12N15/13;
国家 RU
入库时间 2022-08-22 02:13:38

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