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MURINE MONOCLONAL ANTIBODY NMO1, HYBRIDOMA CELLULAR LINE, FRAGMENT OF MURINE MONOCLONAL ANTIBODY (VARIANTS)
MURINE MONOCLONAL ANTIBODY NMO1, HYBRIDOMA CELLULAR LINE, FRAGMENT OF MURINE MONOCLONAL ANTIBODY (VARIANTS)
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机译：鼠单克隆抗体NMO1，杂交细胞系，鼠单克隆抗体片段（变异体）
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摘要
FIELD: molecular biology, immunology, pharmacy. SUBSTANCE: invention relates to a monoclonal antibody NMO1 that shows a specific immunoreactivity with respect to protein HIV-1 gp120 or gp160 and shows capability to neutralize in vitro infection of cells H9 by living strains of HIV-1. NMO1 antibodies are isolated by hybridoma cellular line ATCC N HB 10726. Invention proposes also pharmaceutical compositions that will use for treatment of patients with HIV-1 infection by passive immunization. EFFECT: enhanced effectiveness of antibody and cellular line isolated. 5 cl, 18 dwg, 5 tbl, 9 ex
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机译：领域：分子生物学，免疫学，药学。发明内容本发明涉及一种单克隆抗体NMO1，其对蛋白HIV-1 gp120或gp160表现出特异性的免疫反应性，并具有中和HIV-1活株对H9细胞的体外感染的能力。通过杂交瘤细胞系ATCC N HB 10726分离出NMO1抗体。本发明还提出了用于通过被动免疫治疗HIV-1感染患者的药物组合物。效果：增强抗体和分离的细胞系的有效性。 5厘升，18载重吨，5桶，9吨
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