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Treatment of a trabecular meshwork whose cells are subject to inhibition of cell division with non-steroidal anti-inflammatory drugs

机译:用非甾体类抗炎药治疗小梁网,其细胞受细胞分裂抑制

摘要

The invention concerns the recognition that certain non-steroidal anti-inflammatory agents can overcome or ameliorate limitations on trabecular meshwork cell division produced by environmental stresses (e.g., oxidative or phagocytic injury, or glucocorticoid exposure), and thus can be used to prevent or treat loss of trabecular cells found in certain forms of glaucoma and in normal aging. The use of such non-steroidal anti-inflammatory agents can ameliorate the severity, or prevent glaucoma.
机译:本发明涉及以下认识:某些非甾体抗炎剂可以克服或改善由环境压力(例如,氧化或吞噬性损伤或糖皮质激素暴露)引起的小梁网细胞分裂的局限性,因此可以用于预防或治疗在某些形式的青光眼和正常衰老中发现的小梁细胞丢失。此类非甾体类抗炎药的使用可以减轻严重程度,或预防青光眼。

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