首页>
外国专利>
SYNTHESIS OF NUCLEIC ACIDS OF PEPTIDES OR POLYAMIDES (PNA) USING A PROTECTIVE GROUP OF UNSTABLE AMINO AGAINST WEAK ACIDS.
SYNTHESIS OF NUCLEIC ACIDS OF PEPTIDES OR POLYAMIDES (PNA) USING A PROTECTIVE GROUP OF UNSTABLE AMINO AGAINST WEAK ACIDS.
展开▼
机译：使用不稳定氨基酸对弱酸的保护基团合成肽或聚酰胺（PNA）的核酸。
展开▼
页面导航
摘要
著录项
相似文献
摘要
A PROCESS IS DESCRIBED FOR THE ELABORATION OF OLIGOMEROS PNA OF THE FORMULA WHERE B / X ARE DEFINED AS IN THE DESCRIPTION, R0 MEANS HYDROGENO, ALCANOYL, CICLOALCANOIL, AROIL, HETEROAROIL, OR A GRUPO DE, RESPECTIVELY REPRESENT A REST OF AMINO ACID; KYL ARE RESPECTIVELY A COMPLETE NUMBER FROM 0 TO 10, B IS A NATURAL NATURAL NUCLEOBASE IN NUCLEOTIDE CHEMISTRY OR NATURAL NUCLEOBASE OR ITS FORMS OF MEDICINAL PRODUCTS, OR ALSO A SUBSTITUTE COMPOSITE, Q0 IS HYDROXI AND NH2 COMPLETE FIGURE FROM 1 TO 50. THIS DESCRIBES THE REMAINS OF AMINO ACID AND THE COMPONENTS WHERE PG IS A GROUP OF UNSTABLE AMINO PROTECTION AGAINST WEAK ACIDS AND B '' IS A NUCLEOBASE PROTECTED IN ITS HYDROXY OR EXOCYCLIC FUNCTION. STAGED ACCORDING TO THE SOLID PHASE METHOD ON A POLYMER SUPPORT, WHICH IS EQUIPPED WITH AN ANCHOR GROUP, COUPLED AND AFTER THE FINISHED CONSTITUTION, OBJECTIVE COMPOUNDS ARE OBTAINED BY MEANS OF AN UNFOLDING REACTION FROM THE POLE SUPPORTS. INTERMEDIATE PRODUCTS OF THE OLIGOMER PNA ARE ALSO DESCRIBED AS WELL AS THE PROCESS FOR ITS ELABORATION.
展开▼
