首页> 外国专利> ISOLATED POLYNUCLEOTIDE ENCODING SERUM PARAOXONASE; TRANSFORMED HOST CELL; PRODUCTION OF POLYPEPTIDE SERUM PARAOXONASE

ISOLATED POLYNUCLEOTIDE ENCODING SERUM PARAOXONASE; TRANSFORMED HOST CELL; PRODUCTION OF POLYPEPTIDE SERUM PARAOXONASE

机译：分离的编码核苷酸过氧化物酶的多核苷酸;转换的主机单元;多肽血清过氧化物酶的生产

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摘要

Human serum paraoxonase enzyme and DNA (RNA) encoding such serum paraoxonase enzymes are disclosed. Also provided is the procedure for producing such polypeptides by recombinant techniques. Uses of such polypeptides include their use as an antidote for organophosphate poisoning and to prevent neuronal cell death. Diagnostic assays for identifying mutations in a nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.

机译：公开了人血清对氧磷酶和编码这种血清对氧磷酶的DNA（RNA）。还提供了通过重组技术生产这种多肽的方法。此类多肽的用途包括其用作有机磷酸盐中毒的解毒剂并防止神经元细胞死亡。还公开了用于鉴定编码本发明多肽的核酸序列中的突变和用于检测本发明多肽的改变水平的诊断测定。

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公开/公告号NZ289607A

专利类型
公开/公告日1998-11-25

原文格式PDF
申请/专利权人 HUMAN GENOME SCIENCES INC;
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申请/专利号NZ19950289607
发明设计人 HUDSON PETER L;HE WEI-WU;RUBEN STEVEN M;
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申请日1995-06-28
分类号C12N15/55;C12N15/11;C12N15/10;C12N15/12;C12N15/63;C12N1/21;C12N5/10;C12N9/16;
国家 NZ
入库时间 2022-08-22 02:26:35

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