首页> 外国专利> crystalline forms of endo - 2.3 - dihydro - n - (8 - methyl - 8 - azabicyclo (3.2.1) oct. 3 - yl) - 2 - oxo - 1h - benzimidazole carboxamide hydrochloride monohydrate) and endo - 3 - ethyl - 2.3 - dihydro - n - (8 - methyl - 8 - azabicyclo (3.2.1) oct. 3 - yl) - 2 - oxo - 1h - benzimidazole carboxamide hydrochloride monohydrate) as 5-ht antagonists

crystalline forms of endo - 2.3 - dihydro - n - (8 - methyl - 8 - azabicyclo (3.2.1) oct. 3 - yl) - 2 - oxo - 1h - benzimidazole carboxamide hydrochloride monohydrate) and endo - 3 - ethyl - 2.3 - dihydro - n - (8 - methyl - 8 - azabicyclo (3.2.1) oct. 3 - yl) - 2 - oxo - 1h - benzimidazole carboxamide hydrochloride monohydrate) as 5-ht antagonists

机译：内含物-2.3-二氢-正-（8-甲基-8-氮杂双环（3.2.1）辛基3-基团）-2-氧代-1h-苯并咪唑羧酰胺盐酸盐一水合物的结晶形式和内含物-3-乙基-2.3 -二氢-正丁基-（8-甲基-8-氮杂双环（3.2.1）辛基3-基）-2-羰基-1h-苯并咪唑羧酰胺盐酸盐一水合物）作为5-ht拮抗剂

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Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula CHEM (Compound 2a: R = H (Compound 2b: R = C2H5 the processes for their preparation and pharmaceutical compositions containing them. IMAGE

机译：-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1]辛-3-基）-2-氧代-1H-苯甲杂咪唑-1-羧酰胺盐酸盐的结晶一水合物和式的3-乙基-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1]辛-3-基）-2-氧邻-1H-苯并咪唑-1-羧酰胺盐酸盐（化合物2a：R = H>（化合物2b：R = C2H5>制备方法和含有它们的药物组合物。<图像>

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公开/公告号DE69319955D1

专利类型
公开/公告日1998-09-03

原文格式PDF
申请/专利权人 BOEHRINGER INGELHEIM ITALIA S.P.A. FLORENZ/FIRENZE IT;
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申请/专利号DE19936019955T
发明设计人 CEREDA ENZO I-15057 TORTONA (ALESSANDRIA) IT;DUBINI ENRICA I-20135 MILANO IT;EZHAYA ANTOINE I-20141 MILANO IT;MAFFIONE GRAZIA I-20146 MILANO IT;TURCONI MARCO I-27058 VOGHERA (PAVIA) IT;
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申请日1993-03-19
分类号C07D451/04;A61K31/46;
国家 DE
入库时间 2022-08-22 02:42:35

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