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Determining spatial structure of proteins from analysis of accessibility of protein side chains
Determining spatial structure of proteins from analysis of accessibility of protein side chains
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机译：通过分析蛋白质侧链的可及性确定蛋白质的空间结构
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摘要
The spatial structure of a protein (I) of known primary structure is established by: (a) determining the surface accessibility (SA) of protein side groups; (b) determining conformations that are compatible with SA and physically possible, and (c) forming and refining a structural model. SA is examined by mutagenesis and step (c) involves analysis of conformational energies.
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