首页>
外国专利>
Use of C63 derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin against bacteria resistant to glycopeptide antibiotics
Use of C63 derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin against bacteria resistant to glycopeptide antibiotics
展开▼
机译：34-脱（乙酰氨基葡萄糖）-34-脱氧-替考拉宁的C63衍生物对抵抗糖肽类抗生素的细菌的用途
展开▼
页面导航
摘要
著录项
相似文献
摘要
C63-Amide derivatives of 34-de(acetylglucosaminyl) -34-deoxy-teicoplanin wherein the amide moiety is derived from a di- or poly-amine. The derivatives are prepared by reacting 34-de(acetylglucosaminyl)- 34-deoxy-teicoplanins with an active esters forming reagent such as chloroacetonitrile and then contacting said active esters with the appropriate di- or polyamine. The amide derivatives which are active against Gram-positive microorganisms, in particular against Group A Streptococci were found to be active also against bacteria which are resistant to glycopeptide antibiotics.
展开▼
