首页> 外国专利> Protein polypeptides for use as a toxin nucleotide sequence process to produce a polypeptideo recombinant DNA molecule express vector cell insecticide system insecticide animal plant n the human toxin process to produce an active polypeptide of an inactive polypeptide precursor isolated isolated base sequences isolated nucleotides base sequence siolada new isolated polyptid toxin and new subject or combination

Protein polypeptides for use as a toxin nucleotide sequence process to produce a polypeptideo recombinant DNA molecule express vector cell insecticide system insecticide animal plant n the human toxin process to produce an active polypeptide of an inactive polypeptide precursor isolated isolated base sequences isolated nucleotides base sequence siolada new isolated polyptid toxin and new subject or combination

机译：蛋白多肽，用作毒素核苷酸序列工艺来生产多肽重组DNA分子表达载体细胞杀虫系统杀虫动植物人毒素工艺来生产无活性多肽前体的活性多肽分离的碱基序列分离的核苷酸碱基序列siolada新分离的息肉毒素和新主题或组合

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摘要

The isolation of a protein and the cloning and expression of the corresponding gene which encodes the neurotoxin delta-latroinsectotoxin (delta-LIT) is disclosed. The protein is isolated from the venom of the Black Widow Spider, Latrodectus mactans Tredecimguttatus. The native gene encodes a precursor protein which is non-toxic. Truncation of the gene at both the N-terminus and C-terminus yields a toxic protein which can be expressed in bacterial cells. It is postulated that delta-LIT may be used as an insecticide. In addition, the gene may be introduced and expressed in both plants and non-human animals.

机译：公开了蛋白质的分离以及编码神经毒素δ-latroinsectotoxin（δ-LIT）的相应基因的克隆和表达。该蛋白是从黑寡妇蜘蛛的黑毒蜘蛛的毒液中分离出来的。天然基因编码无毒的前体蛋白。在N端和C端截短该基因会产生一种有毒蛋白质，可以在细菌细胞中表达。据推测，δ-LIT可用作杀虫剂。另外，该基因可以在植物和非人类动物中引入和表达。

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公开/公告号BR9507507A

专利类型
公开/公告日1997-09-02

原文格式PDF
申请/专利权人 BRITISH TECHNOLOGY GROUP LIMITED;
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申请/专利号BR19959507507
发明设计人 DAVID ROBERT BELL;PETER NORMAN RUSSEL USHERWOOD;IRINA DULUBOVA;TATIANA VOLKOVA;EUGENE GRISHIN;VALERY KRASNOPEROV;TATIANA GENRIKHOVNA GALKINA;MIKHAIL VLADIMIRIVICH KHOVOTCHEV;KIRILL ANDREEVICH PLUZHNIKOV;
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申请日1995-04-24
分类号C12N15/12;C12N15/82;C12N15/63;C12N5/10;C07K14/435;A01N63/02;A01H1/00;A01K67/027;C07K1/12;
国家 BR
入库时间 2022-08-22 03:27:38

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