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Apparatus for simulating the effects of a biological given to the release of active ingredient change in the shape of the pharmaceutical dosage moldings, as well as the dissolution behavior, and collapse behavior
Apparatus for simulating the effects of a biological given to the release of active ingredient change in the shape of the pharmaceutical dosage moldings, as well as the dissolution behavior, and collapse behavior
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机译：用于模拟生物制剂对活性成分释放的影响的装置，该制剂在药物剂型中的形状，溶解行为和崩解行为
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摘要
(57) apparatus for simulating the effects of a biological given to the release of active ingredient change in the shape of the [summary] pharmaceutical dosage moldings, as well as the dissolution behavior, and collapse behavior, [synthetic intestinal fluid or synthetic gastric juice for example] the test medium (P) and beaker-type container for housing pharmaceutical dosage molded product (D) (21), and a stirring device suspended from (22) for the test medium (P), projecting pillars shaped platform hanging from (23) become. Vertically and preferably, a stirring device (23) may move in and out in a beaker (21) periodically. (23), comprising a head portion of a piston shape that is disposed (25) piston rod (24), the head portion (24), through holes for the test medium (P) stirring device which reciprocates vertically and and are provided, the distance (24) of the head portion from the floor of the container may vary periodically based on the reciprocating periodic (23) stirrer.
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