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Procedure for determining Porphyromonas gingivalis.
Procedure for determining Porphyromonas gingivalis.
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机译:确定牙龈卟啉单胞菌的程序。
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摘要
It DESCRIBES A METHOD OF DETERMINING Porphyromonas gingivalis (P. gingivalis BEFORE BACTEROIDES gingivalis) in diagnosis and / or treatment of periodontitis, IN WHICH takes a sample from a possible site of P. gingivalis and said sample is added to a composition comprising a substrate subjected to proteolysis, amidolysis O esterolysis AND AT LEAST A trigger for the proteolytic, amidolytic or esterolytic OF ONE OR MORE enzymes P. gingivalis activity on said substrate; Said activator being cysteine, cysteamine, glycine or a dipeptide or tripeptide containing glycine, or an amide or an alkyl ester LOWER glycine dipeptide or tripeptide or the like, or a derivative of such DECARBOXILATADO dipeptide or tripeptide; AND DETERMINATION OF ACTIVITY proteolytic, amidolytic O esterolytic said sample in said composition. IN Figure 1 illustrates the effect of glycyl-glycine ON BAPNA hydrolyzing pH DEPENDENT PROTEINASES PRESENTES ENEXTRACTOS CRUDE P. GINGIVAL. Also describes a kit for use in the method described, comprising a device for collection of a sample from a possible site of P. gingivalis; Said kit comprising the composition further comprising a substrate subjected to proteolysis, amidolysis O esterolysis AND AT LEAST ONE TRIGGER FOR ACTIVITY proteolytic, amidolytic OR ONE OR MORE esterolytic enzymes P. gingivalis on said substrate.
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