首页> 外国专利> Polypeptide nucleic acid molecule hybrid gene vector of replicable expression for the production of a recombinant polypeptide expression system for producing a transgenic non-human mammal capable of expressing a transgenic non-human mammalian BSSL variant progeny of a transgenic non-human mammal milk formula for small children process for producing the same use of a polypeptide pharmaceutical composition and polepeptide Technical field

Polypeptide nucleic acid molecule hybrid gene vector of replicable expression for the production of a recombinant polypeptide expression system for producing a transgenic non-human mammal capable of expressing a transgenic non-human mammalian BSSL variant progeny of a transgenic non-human mammal milk formula for small children process for producing the same use of a polypeptide pharmaceutical composition and polepeptide Technical field

机译：可复制表达的多肽核酸分子杂交基因载体，用于生产重组多肽表达系统，用于生产能够表达转基因非人类哺乳动物奶粉的转基因非人类哺乳动物BSSL变体后代的转基因非人类哺乳动物产生多肽药物组合物和极肽的相同用途的儿童方法技术领域

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摘要

The invention discloses nucleic acids encoding variant Bile Salt Stimulated Lipase (BSSL; EC 3.1.1.1). The encoded variant BSSL enzymes maintain catalytic activity but contain fewer glycosylation sites that full-length BSSL. This reduced glycosylation facilitates purification and characterization of recombinant BSSL proteins.

机译：本发明公开了编码变体胆盐刺激脂肪酶（BSSL; EC 3.1.1.1）的核酸。编码的变异BSSL酶保持催化活性，但比全长BSSL含有更少的糖基化位点。这种减少的糖基化有助于重组BSSL蛋白的纯化和表征。

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公开/公告号BR9406376A

专利类型
公开/公告日1996-01-16

原文格式PDF
申请/专利权人 ASTRA AKTIEBOLAG;
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申请/专利号BR19949406376
发明设计人 LARS BLACKBERG;MICHAEL EDLUND;LENNART HANSSON;OLLE HERNELL;LENNART LUNDBERG;MATS STROMQVIST;JAN TORNELL;
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申请日1994-02-25
分类号C12N9/20;A01K67/027;C12N15/00;
国家 BR
入库时间 2022-08-22 03:54:51

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