首页> 外国专利> Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it

Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it

机译:人骨钙素的免疫测定方法,其试剂和试剂盒,抗人骨钙素的抗体,产生所述抗体的杂交瘤及其产生方法

摘要

A method of immunologically assaying intact human osteocalcin in a human assay sample by using an antibody having an epitope in a region of an amino acid sequence 1 to 20 on the N-termianl side of human osteocalcinand an antibody having an epitope in a region of an amino acid sequence 36 to 49 on the C-terminal side of human osteocalcin. A reagent and a kit therefor. Furthermore, a method of immunologicaslly assaying the total amount of human intact osteocalcin and a reagent thereof in a human assay sample. A reagent and a kit therefor. A monclonal antibody and a polyclonal antibody used for the assay. A process for producing these antibodies, and utilization of these antibodies.
机译:通过使用在人骨钙素的N末端侧氨基酸序列1至20的区域中具有表位的抗体和在人骨钙素的N区域中具有表位的抗体对人测定样品中的完整人骨钙素进行免疫分析的方法人骨钙素C末端的36至49位氨基酸序列。试剂及其试剂盒。此外,提供了一种免疫学方法测定人测定样品中人完整骨钙素及其试剂总量的方法。试剂及其试剂盒。用于测定的单克隆抗体和多克隆抗体。产生这些抗体和利用这些抗体的方法。

著录项

  • 公开/公告号EP0646794A1

    专利类型

  • 公开/公告日1995-04-05

    原文格式PDF

  • 申请/专利权人 TEIJIN LIMITED;

    申请/专利号EP19940113194

  • 申请日1990-02-08

  • 分类号G01N33/82;G01N33/74;G01N33/68;G01N33/577;G01N33/543;C12P21/08;A61K39/395;C07K1/04;

  • 国家 EP

  • 入库时间 2022-08-22 04:12:57

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