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Medicine containing the tissular protein PP4, process for the preparation of PP4 and its pasteurization, and the use of PP4

机译:包含组织蛋白PP4的药物,PP4的制备方法及其巴氏灭菌法以及PP4的用途

摘要

Pasteurisation of a soln. of the placental glycoprotein PP4 comprises heating it, in presence of Ca ions and at least one mono- or oligo-saccharide or sugar alcohol, and opt. also an amino acid, so that pathogenic germs are killed. Treatment is pref. at pH 5-9.5 (6.5-8.5), and the sugar or sugar alcohol is 30-150g/100ml, esp. 100-150g sucrose/100ml. The Ca concn. is 0.005-2, esp. 0.03-0.1, M and the opt. amino acid is 0.1-1.5 M.
机译:巴氏杀菌。胎盘糖蛋白PP4的“制备”包括在Ca离子和至少一种单糖或寡糖或糖醇存在下加热它,然后选择。也是一种氨基酸,可以杀死病原菌。治疗是首选。 pH为5-9.5(6.5-8.5)时,糖或糖醇为30-150g / 100ml,尤其是。 100-150克蔗糖/ 100毫升。钙浓度是0.005-2,尤其是0.03-0.1,M和opt。氨基酸为0.1-1.5M。

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