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Medicine containing the tissular protein PP4, process for the preparation of PP4 and its pasteurization, and the use of PP4
Medicine containing the tissular protein PP4, process for the preparation of PP4 and its pasteurization, and the use of PP4
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机译:包含组织蛋白PP4的药物,PP4的制备方法及其巴氏灭菌法以及PP4的用途
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摘要
Pasteurisation of a soln. of the placental glycoprotein PP4 comprises heating it, in presence of Ca ions and at least one mono- or oligo-saccharide or sugar alcohol, and opt. also an amino acid, so that pathogenic germs are killed. Treatment is pref. at pH 5-9.5 (6.5-8.5), and the sugar or sugar alcohol is 30-150g/100ml, esp. 100-150g sucrose/100ml. The Ca concn. is 0.005-2, esp. 0.03-0.1, M and the opt. amino acid is 0.1-1.5 M.
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