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Fungicidal composition, process for the preparation of a compound, insecticide or acaricide, fungicide method, composition, method of inibicao insects or acaros

机译:杀真菌组合物,化合物的制备方法,杀虫剂或杀螨剂,杀真菌剂的方法,组合物,稻瘟病昆虫或螨的方法

摘要

Compounds of formula (1) CHEM wherein R1 to R4 are independently: H, halo, I, (C1-C4) alkyl, branched (C3-C4) alkyl, halo (C1-C4) alkyl, (C1-C4) alkoxy, halo (C1-C4) alkoxy, NO2, or NH2, at least two of R1 to R4 being H, one of X and Y is N and the other is CR5, or both X and Y are CR5, R5 is H, CH3, or Cl; Z is O, NR6, S, SO, SO2, or CR7R8; R6 is H, (C1-C4) alkyl, or (C2-C4) acyl; R7 and R8 are independently H, (C1-C4) alkyl, branched (C3-C4) alkyl, or (C1-C4) acyl, or R7 and R8 combine to form a saturated or unsaturated carbocyclic ring containing three to seven carbon atoms or one of R7 and R8 can combine with one of R9 and R10 to form a double bond; R9 and R10 are independently H, (C1-C3) alkyl, phenyl, substituted phenyl, (C3-C8) cycloalkyl, hydroxy, halo, I, or acetyl, or R9 and R10 combine to form a saturated or unsaturated carbocyclic ring containing three to seven carbon atoms; and Ar is (C3-C8) cycloalkyl, substituted (C3-C8) cycloalkyl, (C3-C8) cycloalkenyl, naphthyl, dihydronaphthyl, tetrahydronaphthyl, decahydronaphthyl, 1,3-benzodioxolyl, fluorenyl, pyridyl, 2,3-dihydro-1,4-benzodioxin-2-yl, furyl optionally substituted with halo, I, CF3, CN, NO2, (C1-C4) alkyl, branched (C3-C4) alkyl, phenyl, or (C1-C4) alkoxy, thienyl optionally substituted with halo, I, CF3, CN, NO2, (C1-C4) alkyl, branched (C3-C4) alkyl, phenyl, or (C1-C4) alkoxy, a group of the formula (2) or (2a) CHEM wherein R11 is H, halo, I, CF3, CN, NO2, (C1-C4) alkyl, branched (C3-C4) alkyl, phenyl, or (C1-C4) alkoxy, F is N or CH and G is O, NR20, or CH2, provided that F is N or G is NR20, where R20 is H, (C1-C4) alkyl, (C1-C4) acyl, phenylsulfonyl, or substituted phenylsulfonyl; a group of the formula (3) CHEM wherein R12 to R16 are independently H, halo, I, (C1-C10) alkyl, branched (C3-C6) alkyl, halo (C1-C4) alkyl, (C1-C4) alkoxy, halo (C1-C4) alkoxy, phenoxy, substituted phenoxy, phenyl, substituted phenyl, phenylthio, or substituted phenylthio, NO2, NH2, acetoxy, OH, CN, or SiR17R18R19, or OSiR17R18R19, where R17, R18, and R19 are independently C1-C4 alkyl, C1-C4 branched alkyl, phenyl, or substituted phenyl, provided that unless each of R12 to R16 is F, CH3, or H, then at least two of R12 to R16 are H; or an acid addition salt of a compound of formula (1), or an N-oxide of a compound of formula (1) where Y is CR5; provided that if R1 to R4 are all H, X is CR5, Y is N, and Z is NR6, then Ar is naphthyl or a group of formula (3) wherein one of R12 to R16 is phenyl, substituted phenyl, phenoxy, substituted phenoxy, phenylthio, or substituted phenylthio, halo (C1-C4) alkyl, or halo (C1-C4) alkoxy, are plant fungicides, insecticides, and miticides.
机译:式(1)的化合物其中R 1至R 4独立地为:H,卤素,I,(C1-C4)烷基,支链(C3-C4)烷基,卤素(C1-C4)烷基,(C 1 -C 4)烷氧基,卤素(C 1 -C 4)烷氧基,NO 2或NH 2,R 1至R 4中的至少两个为H,X和Y之一为N,另一个为CR < 5或X和Y均为CR 5,R 5为H,CH 3或Cl;或Z为O,NR 6,S,SO,SO 2或CR 7 R 8; R 6为H,(C 1 -C 4)烷基或(C 2 -C 4)酰基。 R 7和R 8独立地为H,(C 1 -C 4)烷基,支链(C 3 -C 4)烷基或(C 1 -C 4)酰基,或R 7和R 8结合形成a含3至7个碳原子或R 7和R 8之一的饱和或不饱和碳环可与R 9和R 1 0之一结合形成双键; R 9和R 1 0独立地为H,(C 1 -C 3)烷基,苯基,取代的苯基,(C 3 -C 8)环烷基,羟基,卤素,I或乙酰基,或R 9和R 1 0结合形成含有3至7个碳原子的饱和或不饱和碳环; Ar是(C3-C8)环烷基,取代的(C3-C8)环烷基,(C3-C8)环烯基,萘基,二氢萘基,四氢萘基,十氢萘基,1,3-苯并二氧戊基,芴基,吡啶基,2,3-二氢-1任选被卤素,I,CF 3,CN,NO 2,(C 1 -C 4)烷基,支链(C 3 -C 4)烷基,苯基或(C 1 -C 4)烷氧基,噻吩基取代的,4-苯并二恶英-2-基,呋喃基被卤素,I,CF3,CN,NO2,(C1-C4)烷基,支链(C3-C4)烷基,苯基或(C1-C4)烷氧基取代的式(2)或(2a)基CHEM>其中R 1 1为H,卤素,I,CF3,CN,NO2,(C1-C4)烷基,支链(C3-C4)烷基,苯基或(C1-C4)烷氧基,F为N或CH且G为O,NR 2 <0>或CH2,条件是F为N或G为NR 2 <0>,其中R 2 <0>为H(C1-C4 )烷基,(C 1 -C 4)酰基,苯磺酰基或取代的苯磺酰基;式(3)的基团:其中R 1 2至R 1 6分别为H,卤素,I,(C1-C10)烷基,支链(C3-C6)烷基,卤素(C1-C4)烷基,(C1-C4)烷氧基,卤素(C1-C4)烷氧基,苯氧基,取代的苯氧基,苯基,取代的苯基,苯硫基或取代的苯硫基,NO2,NH2,乙酰氧基,OH,CN或SiR <1> <7> R <1> <8> R <1> <9>或OSiR <1> <7> R <1> <8> R <1> <9>,其中R <1> <7>,R 1 <8>和R 1 <9>独立地为C 1 -C 4烷基,C 1 -C 4支链烷基,苯基或取代的苯基,条件是除非每个R 1 <2 R 1〜R 6中的R 1为F,CH 3或H,则R 1 2〜R 1 6中的至少两个为H。 Y为CR 5的式(1)化合物的酸加成盐或式(1)化合物的N-氧化物。前提是如果R 1至R 4全部为H,X为CR 5,Y为N,Z为NR 6,则Ar为萘基或式(3)的基团,其中一个为R 1 2至R 1 6为苯基,取代的苯基,苯氧基,取代的苯氧基,苯硫基或取代的苯硫基,卤代(C1-C4)烷基或卤代(C1-C4)烷氧基。植物杀菌剂,杀虫剂和杀螨剂。

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