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DEVELOPMENT FACTOR FOR PRODUCING POLYPEPTIDE, EXCHANGE DEVELOPMENT OF POLYPEPTIDE, HOST CONTAINING DEVELOPMENT VECTOR AND PRODUCT MADE BY SAID HOST

机译：生产多肽，交换多肽的发展，包含发展矢量的宿主和所说宿主生产的产品的发展因素

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摘要

This invention relates to the expression and accumulation of heterologous polypeptides in bacterial cells. Further it relates to microbially produced substances as Met-aprotinin and Met-aprotinin-homologues. Novel E. coli vectors comprising DNA sequences for a gene or multimers of it combined with a synthetic promoter, an operator, an ribosome binding site, a hexapeptide, a transcription terminator. A novel host organism transformed with the vector including synthetic gene coding for protease inhibitor.

机译：本发明涉及异源多肽在细菌细胞中的表达和积累。此外，它涉及微生物产生的物质，如Met-抑肽酶和Met-抑肽酶-同源物。包含与合成启动子，操纵子，核糖体结合位点，六肽，转录终止子结合的基因或其多聚体的DNA序列的新型大肠杆菌载体。用该载体转化的新型宿主生物，包括编码蛋白酶抑制剂的合成基因。

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公开/公告号JPS6312299A

专利类型
公开/公告日1988-01-19

原文格式PDF
申请/专利权人 BAYER AG;
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申请/专利号JP19870085918
发明设计人 BURIGITSUTE FUON BIRUKEN BERUKUMAN;ERUNSUTO AUGUSUTO AUAASUBARUTO;BENNO MIYURAA-HIRU;
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申请日1987-04-09
分类号C07K1/22;A61K38/00;A61P9/00;A61P29/00;C07K14/00;C07K14/81;C12N1/20;C12N9/99;C12N15/00;C12N15/09;C12N15/66;C12N15/67;C12N15/70;C12P21/02;C12R1/19;
国家 JP
入库时间 2022-08-22 07:07:57

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