首页> 外国专利> New, generally applicable antigen (psc - a) against pseudomonas aeruginosa, which is formed as a means for protection against pseudomonas aeruginosa - infection acts

New, generally applicable antigen (psc - a) against pseudomonas aeruginosa, which is formed as a means for protection against pseudomonas aeruginosa - infection acts

机译:抗铜绿假单胞菌的新的,普遍适用的抗原(psc-a),形成为一种针对铜绿假单胞菌的保护手段-感染

摘要

PURPOSE:The titled antibody consisting essentially of a globulin selected from the group comprising IgM globulin and IgG globulin. CONSTITUTION:A human B lymphocyte having antigen-forming ability on common antigen PSC-A of Pseudomonas aeruginosa (molecular weight: 15,000; protein content: 24-55wt%, saccharide content: 3.0-5.0wt%, hexamine content: =1.0wt%; property: light yellow powder; solubility: soluble in water, solution of salt, etc., slightly soluble in methanol, etc.; color reaction: positive in Lowry- Folin reaction, etc., negative in Erson-Morgan reaction, etc.; isoelectric point: PI=3.8-4.3) is infected with Eb virus, varied into a multiplication type capable of carrying out subculture, a clone that produces durably an antibody showing specificity to the PSC-A is selected, and a monoclonal antibody produced by it is collected. The antibody is useful as a reagent for diagnosing rapidly infectious diseases of Pseudomonas aeruginosa or as a preventive or remedy for injection with Pseudomonas aeruginosa.
机译:目的:标题抗体基本上由选自IgM球蛋白和IgG球蛋白的球蛋白组成。组成:对铜绿假单胞菌常见抗原PSC-A具有抗原形成能力的人B淋巴细胞(分子量:15,000;蛋白质含量:24-55wt%,糖含量:3.0-5.0wt%,六胺含量:<= 1.0wt %;性质:浅黄色粉末;溶解度:溶于水,盐溶液等,微溶于甲醇等;显色反应:Lowry-Folin反应等为正,Erson-Morgan反应等为负;等电点:PI = 3.8-4.3)被埃博病毒感染,变为能够进行继代培养的增殖型,选择了能持久产生对PSC-A特异性的抗体的克隆,并产生了单克隆抗体由它收集。该抗体可用作诊断铜绿假单胞菌的快速感染性疾病的试剂或用作注射铜绿假单胞菌的预防剂或治疗剂。

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