首页> 外国专利> Antibiotic susceptibility testing of clinical specimen - transferred to test wells in cartridge holding culture medium and antibiotic

Antibiotic susceptibility testing of clinical specimen - transferred to test wells in cartridge holding culture medium and antibiotic

机译:临床标本的药敏试验-转移到装有培养基和抗生素的药筒中的测试孔中

摘要

A cartridge contains a number of individual wells linked by passages to a filling port. A clinical specimen is introduced into the filler port and fills the wells which are each provided with an overflow cavity to collect air bubbles during the filling operation. The cartridge is transparent and prior to use a pref. freez-dried culture medium is placed in each well so that microorganism growth within a well can be detected optically. Known quantities of antibiotics are introduced into some of the wells while one well contains no antibiotic. After filling the cartridge with the specimen it is incubated and the wells are examined for growth. The apparatus determines the susceptibility of microorganism to an antibiotic without isolating the microorganism. The culture medium will only support the required microorganism and the effectiveness of the antibiotics is detected by comparing the growths in the antibiotic-free well with the remainder. Determination of the effective antibiotic concentration is faster than previously.
机译:药筒包含多个单独的孔,这些孔通过通道链接到填充端口。将临床样本引入填充口并填充孔,每个孔均设有溢流腔,以在填充操作期间收集气泡。墨盒是透明的,在使用前应先取下。将冷冻干燥的培养基置于每个孔中,以便可以光学检测孔中的微生物生长。已知数量的抗生素被引入到一些孔中,而一个孔中则不含抗生素。用标本填充药筒后,将其孵育并检查孔的生长。该设备无需分离微生物即可确定微生物对抗生素的敏感性。培养基将仅支持所需的微生物,并且通过将无抗生素的孔中的生长与其余的进行比较来检测抗生素的有效性。有效抗生素浓度的测定比以前更快。

著录项

  • 公开/公告号IT1121653B

    专利类型

  • 公开/公告日1986-04-10

    原文格式PDF

  • 申请/专利权人 MCDONNELL DOUGLAS CORPORATION;

    申请/专利号IT19760048550

  • 发明设计人

    申请日1976-03-12

  • 分类号G01H;

  • 国家 IT

  • 入库时间 2022-08-22 07:39:18

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