首页> 外国专利> seen framstella new anthracycline glykosid - antibiotics, benemnda ma 144 m 711 and 712 144 ma m, by cultivation of streptomyces galilaeus ma 144 m 711 or streptomyces sp mu 505 - he1 and extraction and purification of the formed

seen framstella new anthracycline glykosid - antibiotics, benemnda ma 144 m 711 and 712 144 ma m, by cultivation of streptomyces galilaeus ma 144 m 711 or streptomyces sp mu 505 - he1 and extraction and purification of the formed

机译：通过培养加利链霉菌ma 144 m 711或streptomyces sp mu 505-he1并对其进行提纯和提纯，可以看到新的蒽环类氨苄青霉素-抗生素贝尼姆达（Benemnda ma 144 m 711和712 144 mam）。

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摘要

New antitumor agents designated MA 144-M1 and MA 144-M2, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria, e.g. Staphyococcus aureus, Bacillus subtilis and Sarcina lutea, and inhibit the growth of animal tumors such as leukemia L 1210, P 388 and sarcoma 180 are produced by fermentation of MA 144-producing strains of streptomyces and by the chemical or enzymatic conversion of aclacinomycin A or cinerubin A.

机译：命名为MA 144-M1和MA 144-M2的新抗肿瘤药是蒽环类糖苷，可抑制革兰氏阳性细菌的生长。通过发酵产MA 144的链霉菌菌株并通过化学或酶促转化阿克拉霉素A或cinerubin A.

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公开/公告号SE436758B

专利类型
公开/公告日1985-01-21

原文格式PDF
申请/专利权人 MICROBIAL CHEM RES FOUND;
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申请/专利号SE19770003760
发明设计人 1)H * UMEZAWA;2)T * TAKEUCHI;3)H * NAGANAWA;4)M * ISHIZUKA;5)N * SHIBAMOTO;6)T * OKI;7)T * INUI;
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申请日1977-03-31
分类号C12P19/56;C07H15/24;
国家 SE
入库时间 2022-08-22 08:11:57

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