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prostacyclin analogues and their use in the inhibition of platelet aggregation induced by arachidonic acid and the broncostenosi
prostacyclin analogues and their use in the inhibition of platelet aggregation induced by arachidonic acid and the broncostenosi
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机译：前列环素类似物及其在抑制花生四烯酸和支气管哮喘引起的血小板凝集中的应用
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摘要
Prostacyclin analogs are provided having the structure IMAGE wherein X represents =O or OH, R1 and R2 are OH or H, provided at least one of R1 and R2 is other than hydroxyl, R3 is H or alkyl of 1 to 4 carbons, m is an integer of from 2 to 5, and n is an integer of from 2 to 10, or pharmaceutically acceptable salts thereof. These compounds have been found to be potent inhibitors of arachidonic acid-induced platelet aggregation and bronchoconstriction.
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