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8-aminotheophyllines - with coronary - vasodilator bronchodilator diuretic, spasmolytic, antiinflammatory and analgesic activity
8-aminotheophyllines - with coronary - vasodilator bronchodilator diuretic, spasmolytic, antiinflammatory and analgesic activity
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机译:8-氨基茶碱-具有冠状动脉-血管扩张剂,支气管扩张剂的利尿,解痉,抗炎和镇痛作用
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摘要
Cpds of formula: their metallic and acid-addn salts (where R=alkyl, hydroxyalkyl, haloalkyl, benzyl, opt. ring substd =1 alkoxy, gp. phenethyl substd by =1 alkoxy gp. or the gp R1 is 1-6C alkyl, phenyl, phenethyl benzyl substd in the nucleus by =1 alkoxy, OH, NO2, NH2 or halogen 3,4-methylenedioxybenzyl, the gp: 2-furfuryl; the gp. -Alk-(4-alkylpiperidinyl); or R and R1 with the attached N-atom form a 4-R4-piperazinyl, 4-R4-piperidyl or 3-hydroxyalkylpyrrolidinyl gp; R2=1-6C alkyl, R3=H 1-6C alkyl or 8-theophyllinyl; R4=Et hydroxyalkyl, phenyl benzyl, Alk=alkylene; provided that R is not hydroxyalkyl when R1 is alkyl or phenethyl and R1 is not alkyl when R is benzl). Cpds are used in human or veterinary medicine.
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