(+)-2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable thereof Pharmaceutical compositions and single unit dosage forms of the stereoisomers, prodrugs, salts, solvates, hydrates or clathrates of which to be obtained are provided herein. Methods of treating, managing or preventing various diseases or disorders are also provided. The compound is known as Apremilast and has the following structural formula. 展开▼