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BIOREACTOR OR FERMENTER FOR THE CULTURING OF CELLS OR MICROORGANISMS IN SUSPENSION IN INDUSTRIAL SCALE
BIOREACTOR OR FERMENTER FOR THE CULTURING OF CELLS OR MICROORGANISMS IN SUSPENSION IN INDUSTRIAL SCALE
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机译：生物反应器或发酵罐用于培养工业规模悬浮液中的细胞或微生物
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摘要
The present disclosure is directed to a bioreactor or fermenter for the culturing of cells or microorganisms in suspension in a liquid medium in industrial scale comprising a vessel containing the culture in a liquid medium having a determined filling height; a stirrer provided in the vessel to stir the liquid medium; a first sparger aranged in the bottom portion of the vessel; and a second or optional more spargers provided above the first sparger to supply additional air bubbles and/or additional oxygen gas bubbles continuously to the liquid medium whereby the second sparger is located at a position in the bioreactor or fermenter above the first sparger in a predefined distance ɳ. It is also described a process for the independent management of dissolved CO2 and O2, by selecting a suitable modified gas flow rate qmod.
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机译：本公开涉及生物反应器或发酵罐，用于培养在工业规模中的液体介质中悬浮液中的细胞或微生物，其包含含有确定的填充高度的液体介质中的容器;在容器中提供的搅拌器搅拌液体培养基;在容器的底部中植入的第一个喷射器;和第一或可选的更多旋光器，在第一喷射器上方，以将额外的气泡和/或额外的氧气气泡连续地供应到液体介质，由此第二喷射器位于预定义的第一喷射器上方的生物反应器或发酵罐中的位置。距离ɳ。还描述了通过选择合适的改进的气流Q mod 来描述溶解CO 2 和O 2 的过程。
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