首页> 外国专利> HEPARAN SULFATE (HS) OLIGOSACCHARIDES EFFECT IN LIVER ISCHEMIA REPERFUSION INJURY

HEPARAN SULFATE (HS) OLIGOSACCHARIDES EFFECT IN LIVER ISCHEMIA REPERFUSION INJURY

机译:硫酸乙酰肝素(HS)低聚糖在肝脏缺血再灌注损伤中的影响

摘要

Disclosed is a method of treating liver ischemia reperfusion (I/R) injury in a subject. In some aspects, the method comprises providing a subject suffering from liver I/R injury or at risk of suffering liver I/R injury; and administering to the subject one or more heparan sulfate (HS) compounds. In some aspects, the one or more HS compounds comprises about 5 to about 18 saccharide units, optionally about 12 to about 18 saccharide units. In some aspects, the one or more HS compounds comprises about 12 saccharide units.
机译:公开了一种治疗受试者肝脏缺血再灌注(I / R)损伤的方法。在一些方面,该方法包括提供患有肝脏I / R损伤的受试者或有患肝I / R损伤的风险;并向受试者施用一种或多种硫酸乙酰肝素(HS)化合物。在一些方面,一种或多种HS化合物包含约5至约18个糖单元,任选地约为12至约18个糖单位。在一些方面,一种或多种HS化合物包含约12个糖单元。

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