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antigen binding molecule capable of binding to CD3 and CD137 but not simultaneously
antigen binding molecule capable of binding to CD3 and CD137 but not simultaneously
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机译:抗原结合分子能够结合CD3和CD137但不同时结合
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摘要
The present invention provides an antigen-binding molecule that binds to CD3 and CD137 (4-1BB); a composition comprising the antigen-binding molecule of interest; and how to use it. The present invention provides an antibody variable region capable of binding CD3 and CD137 (4-1BB) but not simultaneously binding CD3 and CD137, and a variable region that binds to a third antigen different from CD3 and CD137, Antigen-binding molecules are provided. Such antigen binding molecules exhibit enhanced T cell dependent cytotoxic activity induced by these antigen binding molecules through binding to three different antigens.
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