PI3 BTK Composition comprising PI3 kinase inhibitor and BTK inhibitor

• 1. 含有PDE4抑制剂和PI3δ或双重PI3δ-γ激酶抑制剂的药物组合物 [P] . 中国专利： CN104870017B . 2020.08.14
• 2. 含有PDE4抑制剂和PI3 δ或双重PI3 δ-γ激酶抑制剂的药物组合物 [P] . 中国专利： CN111904962A . 2020-11-10
• 3. COMPOSITION COMPRISING PI3 KINASE INHIBITOR AND BTK INHIBITOR [P] . WO2021182903A1 . 2021-09-16

  机译： 包含PI3激酶抑制剂和BTK抑制剂的组合物

• 4. Pharmaceutical composition comprising a PDE4 inhibitor and a PI3δ inhibitor or a dual PI3δ-γ kinase inhibitor [P] . 日本专利： JP6434416B2 . 2018-12-05

  机译： 包含PDE4抑制剂和PI3δ抑制剂或双重PI3δ-γ激酶抑制剂的药物组合物

• 5. Pharmaceutical composition comprising a PDE4 inhibitor and a PI3δ inhibitor or a dual PI3δ-γ kinase inhibitor [P] . 日本专利： JP2015536973A . 2015-12-24

  机译： 包含PDE4抑制剂和PI3δ抑制剂或双重PI3δ-γ激酶抑制剂的药物组合物

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• 5. A key tryptophan in the Tec-family tyrosine kinase Btk allosterically regulates kinase activation [C] . Thomas E. Wales, Raji E. Joseph, Amy H. Andreotti, ASMS Conference on Mass Spectrometry and Allied Topics . 2015
• 6. Mechanistic PK/PD Modeling of Btk Inhibitors and the Development of PET Tracers for Bacterial Infection Diagnosis [D] . Zhang, Zhuo. 2017
• 7. Expression of Functional Sphingosine-1 Phosphate Receptor-1 Is Reduced by B Cell Receptor Signaling and Increased by Inhibition of PI3 Kinase δ but Not SYK or BTK in Chronic Lymphocytic Leukemia Cells [O] . Kathleen J. Till, Andrew R. Pettitt, Joseph R. Slupsky -1
• 8. Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukaemia cells [O] . Till, K, Pettitt, A, Slupsky, J 2015
• 9. Identification and Targeting of Upstream tyrosine Kinases Mediating PI3 Kinase Activation in PTEN Deficient Prostate Cancer [R] . Balk, S. P. 2011

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