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METHODS FOR INTEGRATING DNA INTO GENES WITH GAIN-OF-FUNCTION OR LOSS-OF-FUNCTION MUTATIONS
METHODS FOR INTEGRATING DNA INTO GENES WITH GAIN-OF-FUNCTION OR LOSS-OF-FUNCTION MUTATIONS
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机译:将DNA与功能增益或功能丧失突变集成到基因的方法
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摘要
Methods and compositions for modifying the 3' untranslated region or coding sequence of endogenous genes using rare-cutting endonucleases and donor molecules. The methods and compositions described herein can be used to modify the coding sequence of endogenous genes or to facilitate early termination of transcripts.
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