首页> 外国专利> Hydroxypropyl Starch For Preparing Empty Capsules And Hydroxypropyl Starch-Based Soft Capsules

Hydroxypropyl Starch For Preparing Empty Capsules And Hydroxypropyl Starch-Based Soft Capsules

机译:用于制备空胶囊和羟丙基淀粉的软胶囊的羟丙基淀粉

摘要

This invention comprising in hydroxypropyl starch for preparing empty capsules in alimentary and medical use, and hydroxypropyl starch-based soft capsules. This invention takes water as solvent, mix with propylene epoxide and catalyst for reaction, after washing, drying, hydroxypropyl starch is completed. The MS level of substitution of starch is around 2˜5, gelatinization point between 25˜60° C. After the hydroxypropyl starch is gelatinized by heating in water, a hydroxypropyl starch matrix soft capsule can be prepared. The invention consists in introducing hydroxypropyl by modifying the molecular chain of starch to improve the flexibility and hydrophilicity of starch. Therefore, a hydroxypropyl starch matrix soft capsule capable of preparing a flexible and disintegrating property is provided.
机译:本发明包含在羟丙基淀粉中用于制备消化物和医用用途的空胶囊,以及羟丙基淀粉基软胶囊。 本发明将水作为溶剂,与丙烯环氧化物和反应催化剂混合,洗涤,干燥后,羟丙基淀粉完成。 淀粉的MS水平约为2~5,凝胶化点在25〜60℃之间通过在水中加热凝胶化后,可以制备羟丙基淀粉基质软胶囊。 本发明通过改变淀粉的分子链来提高淀粉的柔韧性和亲水性来提高羟丙基。 因此,提供了能够制备柔性和崩解性的羟丙基淀粉基质软胶囊。

著录项

  • 公开/公告号US2021332156A1

    专利类型

  • 公开/公告日2021-10-28

    原文格式PDF

  • 申请/专利权人 HUNAN ER-KANG PHARMACEUTICAL CO. LTD.;

    申请/专利号US202016857538

  • 发明设计人 FANGWEN SHUAI;

    申请日2020-04-24

  • 分类号C08B31/12;A61K9/48;

  • 国家 US

  • 入库时间 2022-08-24 21:57:48

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