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Evaluation of differentiation resistance of undifferentiated cells

机译：未分化细胞分化抗性评价

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摘要

In the stage of undifferentiated cells, we propose a method to predict the possibility of undifferentiated cells when cells differentiate. The differentiation resistance of undifferentiated cells is evaluated by measuring (I) and / or (II) below.Expression level and / or promoter activity of at least one gene selected from the group consisting of (I) ZNF 354c, C12 orf56, ZNF 578, dppp6 and mirrThe methylation state of the promoter of at least one gene selected from the group consisting of (II) znf355c, c12orf56, ZNF 578, dppp6 and mir886

机译：在未分化细胞的阶段，我们提出了一种方法来预测当细胞分化时未分化的细胞的可能性。通过测量（i）和/或（ii）评估未分化的细胞的分化抗性。表达水平和/或启动子活性，其至少一种选自（i）ZnF 354c，c12 orf56，ZnF 578的基因，DPPP6和镜子中选自（II）ZNF355C，C12ORF56，ZNF 578，DPPP6和MIR886组成的至少一种基因的甲基化状态

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公开/公告号JPWO2020149391A1

专利类型
公开/公告日2021-12-09

原文格式PDF
申请/专利权人公立大学法人横浜市立大学;
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申请/专利号JP20200566493
发明设计人谷口英樹;関根圭輔;
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申请日2020-01-17
分类号C12Q1/68;C12Q1/6869;C12Q1/686;C12Q1/6851;G01N33/68;G01N33/50;G01N33/53;C12N15/09;
国家 JP
入库时间 2022-08-24 22:44:08

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