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Oxadiazole derivatives for the treatment of genetic diseases due to nonsense mutations

机译:氧代唑衍生物治疗遗传疾病引起的义义突变

摘要

Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.
机译:被公开的氧代唑衍生物,它们作为药物的用途,特别是用于治疗基因中基因中的胡说突变的疾病或mRNA中过早的止血沉积件,包含所述恶二唑衍生物和前药或其混合物的药物制剂及其 制备所述恶二唑衍生物的方法。

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