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OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS

机译:乙二唑衍生物用于无意义突变引起的遗传性疾病的治疗

摘要

Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.
机译:公开了恶二唑衍生物,其作为药物的用途以及特别是用于治疗与基因中的无义突变或mRNA中的过早终止密码子的存在有关的疾病,包含所述恶二唑衍生物和前药或其混合物的药物制剂和所述恶二唑衍生物的制备方法。

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