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MITIGATION AND REVERSAL OF FIBROSIS AND INFLAMMATION BY INHIBITION OF TL1A FUNCTION AND RELATED SIGNALING PATHWAYS
MITIGATION AND REVERSAL OF FIBROSIS AND INFLAMMATION BY INHIBITION OF TL1A FUNCTION AND RELATED SIGNALING PATHWAYS
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机译:TL1A函数抑制和相关信号通路的缓解和逆转纤维化和炎症
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摘要
The present invention relates to methods of treating fibrosis and inflammatory bowel disease. In one embodiment, the present invention treats intestinal inflammation by administering to an individual a therapeutically effective dosage of a TL1A inhibitor and/or a DR3 inhibitor. In another embodiment, the invention provides a method of reversing tissue fibrosis in a subject by inhibiting TL1A-DR3 signaling function.
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