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首页> 外国专利> METHOD FOR PREDICTING NEUROLOGICAL RECOVERY FROM THE 14TH TO THE 90TH DAYS OF ISCHEMIC STROKE OF THE BRAIN

METHOD FOR PREDICTING NEUROLOGICAL RECOVERY FROM THE 14TH TO THE 90TH DAYS OF ISCHEMIC STROKE OF THE BRAIN

机译：从脑缺血性脑卒中的第14天预测神经恢复的方法

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FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to neurology, and can be used for prediction of neurological recovery of patients in period from 14th to 90th days of ischemic stroke of brain. For this purpose, on the 14th day of acute ischemic stroke, serum concentrations of the basic myelin protein (MBP), antibodies to it (anti-MBP), vascular endothelial growth factor (VEGF), brain neurotrophic factor (BDNF) are determined, functional independence on the Phekin scale (mRS) and neurological deficiency on the Stroke Scale (SSS) scale is evaluated. The probability of neurological recovery of F on the 90th day in accordance with the developed formula is then considered. If F > 0.5, a high probability of neurological recovery from the 14th to the 90th day of ischemic stroke is predicted, if F < 0.5, the patient is unlikely to be reduced.;EFFECT: method makes it possible to carry out combined assessment of activity of processes of neurogenesis and angiogenesis, protective-compensatory, humoral reactions and degree of damage of myelin sheath of corticospinal tracts and can be possible to solve the problem of dosed rehabilitation interventions in early recovery period of ischemic stroke, which is most sensitive from point of view of structural and synaptic neuroplasticity, and also allows to achieve regression of neurological deficiency and increase functional independence personalised for each patient.;1 cl, 2 dwg, 2 tbl, 2 ex
机译：田地：药物。物质：发明涉及药物，即神经内科，并且可用于预测脑缺血性脑卒中缺血性脑卒中的第14至第90天的患者的神经恢复。为此目的，在急性缺血性中风的第14天，确定碱性髓鞘蛋白（MBP），抗体（抗MBP），血管内皮生长因子（VEGF），脑神经营养因子（BDNF）的血清浓度，评估了Phekin规模（MRS）和中风尺度（SSS）规模上的神经学缺陷的功能独立性。然后考虑了根据发育式公式的第90天的F神经恢复的概率。如果F> 0.5，则预测从第14次至第90天到第90天的神经恢复的高概率，如果F <0.5，则不太可能降低患者。;效果：方法使得能够进行组合评估神经发生和血管生成的过程的活性，皮质脊髓瘤髓鞘的保护性补偿，体液反应和损伤程度，可以解决缺血性卒中早期恢复期的提出康复干预问题，这对Point最敏感结构和突触神经塑性的看法，也可以实现神经系统缺乏的回归，并增加针对每位患者的个性化的功能独立性。; 1 cl，2 dwg，2 tbl，2前

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