INFLUENCE OF DIFFERENT CYCLODEXTRINS ON PROLIFERATION OF HaCaT KERATINOCYTES MEASURED BY MEANS OF BIOLUMINESCENCE AND FLUOROMETRIC ASSAYS

机译：生物发光和荧光法测定不同环糊精对HaCaT角质形成细胞增殖的影响

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Cyclodextrins are cyclic oligosaccharides formed by 6, 7 or 8 α-D(+)-glucopyranose units and described as α-, β-, and γ -cyclodextrin (α-CD, β-CD, γ-CD). Because of their structure, cyclodextrins are able to form internal and low polarized cavities. In this way many organic compounds can be included in cyclodextrins. Such kinds of ligand ―receptor complexes can be used for different applications, e.g. for a transdermal therapeutic system (TTS). The aim of the present study was the investigation of the cytotoxicity of the different cyclodextrins using HaCaT keratinocytes, the influence on the cell proliferation and the determination of non-toxic cyclodextrin concentrations.

机译：环糊精是由6、7或8个α-D（+）-吡喃葡萄糖单元形成的环状寡糖，被描述为α-，β-和γ-环糊精（α-CD，β-CD，γ-CD）。由于其结构，环糊精能够形成内部和低极化的腔体。这样，许多有机化合物可以包含在环糊精中。这类配体-受体复合物可用于不同的应用，例如用于经皮治疗系统（TTS）。本研究的目的是使用HaCaT角质形成细胞研究不同环糊精的细胞毒性，对细胞增殖的影响以及确定无毒环糊精浓度的方法。

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来源
《12th Symposium on Bioluminescence and Chemiluminescence, Apr 5-9, 2002, Robinson College, University of Cambridge, UK》|2002年|p.479-482|共4页
会议地点 Cambridge(GB)
作者
C HIPLER; U-CH HIPLER; P ELSNER; U WOLLINA;
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作者单位

Department of Dermatology, Friedrich-Schiller-University of Jena, D-07743 Jena;

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原文格式 PDF
正文语种 eng
中图分类生物物理学;
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1. Influence of cyclodextrins on the proliferation of HaCaT keratinocytes in vitro [J] . U. C. Hipler, U. Schonfelder, C. Hipler Journal of biomedical materials research, Part A . 2007,第1期

机译：环糊精对HaCaT角质形成细胞体外增殖的影响
2. Influence of cyclodextrins on the proliferation of HaCaT keratinocytes in vitro. [J] . Hipler UC, Schonfelder U, Hipler C, Journal of biomedical materials research, Part A . 2007,第1期

机译：环糊精对HaCaT角质形成细胞体外增殖的影响。
3. Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in HaCaT keratinocytes [J] . Petersen AB., Vicanova J., Thorn T., Journal of Photochemistry and Photobiology, B. Biology: Official Journal of the European Society for Photobiology . 2000,第1a3期

机译：过氧化氢是由HaCaT角质形成细胞中的碱性彗星试验测量的UVA诱导的DNA损伤的原因
4. INFLUENCE OF DIFFERENT CYCLODEXTRINS ON PROLIFERATION OF HaCaT KERATINOCYTES MEASURED BY MEANS OF BIOLUMINESCENCE AND FLUOROMETRIC ASSAYS [C] . C HIPLER, U-CH HIPLER, P ELSNER, Symposium on bioluminescence and chemiluminescence . 2002

机译：不同环糊精对通过生物发光和荧光测定测量的HaCAT角质形成细胞增殖的影响
5. Part I. Highly sensitive hybridization assays for prostate-specific antigenmRNA based on time-resolved fluorescence and bioluminescence. Part II. Fluorometric and time-resolved immunofluorometric assays for protein-tyrosine phosphatase and kinase activity. [D] . Galvan, Barbara. 1996

机译：第一部分：基于时间分辨荧光和生物发光的前列腺特异性抗原mRNA的高灵敏杂交检测。第二部分用于蛋白质酪氨酸磷酸酶和激酶活性的荧光测定法和时间分辨免疫荧光测定法。
6. Hyperforin/HP-β-Cyclodextrin Enhances Mechanosensitive Ca2+ Signaling in HaCaT Keratinocytes and in Atopic Skin Ex Vivo Which Accelerates Wound Healing [O] . Hiroya Takada, Jun Yonekawa, Masami Matsumoto, 2006

机译：Hyperforin /HP-β-环糊精可增强HaCaT角质形成细胞和异位性皮肤离体中机械敏感的Ca2 +信号传导，从而加速伤口愈合。
7. Part I. Highly sensitive hybridization assays for prostate-specific antigenmRNA based on time-resolved fluorescence and bioluminescence. Part II. Fluorometric and time-resolved immunofluorometric assays for protein-tyrosine phosphatase and kinase activity. [O] . Galvan Barbara. 1996

机译：第一部分：基于时间分辨荧光和生物发光的前列腺特异性抗原mRNA的高灵敏杂交检测。第二部分用于蛋白质酪氨酸磷酸酶和激酶活性的荧光测定法和时间分辨免疫荧光测定法。
8. Fluorometric Assay for Intracellular pH in Human Epidermal Keratinocytes [R] . DEJoseph, M. E. , Smith, W. J. 2000

机译：人表皮角质形成细胞中细胞内pH的荧光测定

INFLUENCE OF DIFFERENT CYCLODEXTRINS ON PROLIFERATION OF HaCaT KERATINOCYTES MEASURED BY MEANS OF BIOLUMINESCENCE AND FLUOROMETRIC ASSAYS

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