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首页> 外文会议>2001 TMS Annual Meeting on Structural Biomaterials for the 21st Century, Feb 11-12, 2001, New Orleans, LA >Evaluation of Mechanical Properties and Biocompatibility of Cast Titanium with Silicon Addition
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Evaluation of Mechanical Properties and Biocompatibility of Cast Titanium with Silicon Addition

机译：添加硅对铸钛力学性能和生物相容性的评价

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摘要

In order to develop a new kind of medical implant material, the mechanical properties and biocompatibility of Ti-Si cast alloys prepared by dental casting machine have been studied. The results show that silicon addition significantly modified the microstructure of the titanium alloys. In addition, Ti-Si alloys show a good combination of strength and ductility in a wide range of silicon content in contrast to the pure titanium and Ti-6Al-4V alloy. A dense and uniform bonelike apatite layer is formed on the surface of substrate of the Ti-Si alloy soaked in simulated body fluid for 4 weeks. The apatite-forming ability is higher than that of pure titanium. The in vitro cytotoxicity of Ti-Si alloy is also assessed in a HepG2 cell assay. Ti-Si alloy exhibits the same cytocompatibility with pure titanium after testing the HepG2 cells cultured with the extraction of Ti-Si alloy. It has been revealed that Ti-Si cast alloys can be expected as promising candidates for dental application because of a good balance between mechanical properties and biocompatibility.
机译：为了开发一种新型的医用植入材料，对牙科铸造机制备的Ti-Si铸造合金的力学性能和生物相容性进行了研究。结果表明，硅的添加显着改变了钛合金的微观结构。此外，与纯钛和Ti-6Al-4V合金相比，Ti-Si合金在广泛的硅含量范围内显示出强度和延展性的良好组合。浸泡在模拟体液中4周的Ti-Si合金基底表面形成致密且均匀的骨状磷灰石层。形成磷灰石的能力高于纯钛。 Ti-Si合金的体外细胞毒性也在HepG2细胞分析中进行了评估。测试提取Ti-Si合金后培养的HepG2细胞后，Ti-Si合金与纯钛具有相同的细胞相容性。已经发现，由于机械性能和生物相容性之间的良好平衡，可以预期将Ti-Si铸造合金用作牙科应用的有前途的候选材料。

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