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Evaluation of Mechanical Properties and Biocompatibility of Cast Titanium with Silicon Addition

机译:硅加成评价铸钛力学性能和生物相容性

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In order to develop a new kind of medical implant material, the mechanical properties and biocompatibility of Ti-Si cast alloys prepared by dental casting machine have been studied. The results show that silicon addition significantly modified the microstructure of the titanium alloys. In addition, Ti-Si alloys show a good combination of strength and ductility in a wide range of silicon content in contrast to the pure titanium and Ti-6Al-4V alloy. A dense and uniform bonelike apatite layer is formed on the surface of substrate of the Ti-Si alloy soaked in simulated body fluid for 4 weeks. The apatite-forming ability is higher than that of pure titanium. The in vitro cytotoxicity of Ti-Si alloy is also assessed in a HepG2 cell assay. Ti-Si alloy exhibits the same cytocompatibility with pure titanium after testing the HepG2 cells cultured with the extraction of Ti-Si alloy. It has been revealed that Ti-Si cast alloys can be expected as promising candidates for dental application because of a good balance between mechanical properties and biocompatibility.
机译:为了开发一种新型的医用植入物材料的,机械性能和Ti-Si组成的生物相容性铸造合金制备牙科铸造机进行了研究。结果表明,除硅改性显著的钛合金的微结构。此外,钛 - 硅合金显示的强度和延展性的在宽范围的对比的纯钛和Ti-6Al-4V合金的硅含量的良好结合。是形成Ti-Si合金的基体的表面上形成致密且均匀的骨样磷灰石层浸泡在模拟体液4周。的磷灰石形成能力比纯钛更高。的Ti-Si合金的体外细胞毒性也进行了评估在HepG 2细胞测定法。的Ti-Si合金测试用的Ti-Si合金的提取培养的HepG2细胞后表现出与纯钛相同细胞相容性。据透露,钛硅铸造合金可以预期的前途,因为机械性能和生物相容性之间的良好平衡的牙科应用的候选人。

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