The Lab-on-PCB framework for affordable, electronic-based point-of-care diagnostics: From design to manufacturing

机译：PCB上的Lab-on-PCB框架，用于价格合理的基于电子的即时诊断：从设计到制造

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摘要

A novel, Lab-on-Printed Circuit Board (LoPCB) manufacturing technology is demonstrated for the development of low-cost electrochemical biosensors combined with microfluidics for Point-of-Care (PoC) applications. An analysis of the developed PCB architecture is presented, detailing the three development areas of the proposed LoPCB platform, i.e. microfluidics, biosensors and electronics. Design rules and potential fabrication limitations are also discussed, based on the characterization of prototype fabricated systems. Two PCB-based devices have been designed and fabricated, a microfluidic active diluter with a variable and actively controlled dilution ratio and an electrochemical biosensor. The obtained results demonstrate the feasibility of a complete LoPCB platform, where all three compartments will co-exist and co-operate, providing an electronic-based PoC system for electrochemical biosensing.

机译：演示了一种新颖的印制电路板制造（LoPCB）制造技术，该技术可用于结合护理点（PoC）应用的低成本微流控电化学生物传感器的开发。本文对已开发的PCB架构进行了分析，详细介绍了拟议的LoPCB平台的三个开发领域，即微流体，生物传感器和电子产品。基于原型制造系统的特性，还讨论了设计规则和潜在的制造限制。已经设计和制造了两种基于PCB的设备，一种具有可变且主动控制的稀释比的微流体活性稀释器和一个电化学生物传感器。获得的结果证明了完整的LoPCB平台的可行性，其中所有三个隔室将共存并合作，从而提供了基于电子的PoC系统用于电化学生物传感。

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来源
《2016 IEEE Healthcare Innovation Point-Of-Care Technologies Conference》|2016年|126-129|共4页
会议地点 Cancun(MX)
作者
N. Vasilakis; K. I. Papadimitriou; D. Evans; H. Morgan; T. Prodromakis;
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作者单位

Nanofabrication Centre, School of Electronics and Computer Science, University of Southampton, SO17 1BJ, U.K.;

Nanofabrication Centre, School of Electronics and Computer Science, University of Southampton, SO17 1BJ, U.K.;

Nanofabrication Centre, School of Electronics and Computer Science, University of Southampton, SO17 1BJ, U.K.;

Nanofabrication Centre, School of Electronics and Computer Science, University of Southampton, SO17 1BJ, U.K.;

Nanofabrication Centre, School of Electronics and Computer Science, University of Southampton, SO17 1BJ, U.K.;

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会议组织
原文格式 PDF
正文语种 eng
中图分类
关键词
Microfluidics; Biosensors; Electrodes; Manufacturing; Temperature sensors; MOSFET;

机译：微流控;生物传感器;电极;制造;温度传感器; MOSFET;

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机译：实验室PCB框架实惠，基于电子的护理点诊断：从设计到制造

The Lab-on-PCB framework for affordable, electronic-based point-of-care diagnostics: From design to manufacturing

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