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KINEMATICS AND WORKSPACE ANALYSIS OF PROTEIN BASED NANO-MOTORS

机译:基于蛋白质的纳米电机的运动学和工作空间分析

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摘要

Kinematic and workspace analyses are performed to predict the performance of a new nanoscale biomolecular motor: The Viral Protein Linear (VPL) Motor. The motor is based on a conformational change observed in a family of viral envelope proteins when subjected to a changing pH environment. The conformational change produces a motion of about 10 nm, making the VPL a basic linear actuator, which can be further interfaced with other organic/inorganic nanoscale components such as DNA actuators and carbon nanotubes. This paper presents the principle of operation of the VPL motor and the development of direct and inverse kinematic models for workspace analysis. Preliminary results obtained from the developed computational tools are presented.
机译:运动学和工作区分析可以预测新型纳米级生物分子马达的性能:病毒蛋白线性(VPL)马达。该马达基于在不断变化的pH环境下在病毒包膜蛋白家族中观察到的构象变化。构象变化产生约10 nm的运动,使VPL成为基本的线性致动器,可以进一步与其他有机/无机纳米级组分(例如DNA致动器和碳纳米管)连接。本文介绍了VPL电动机的工作原理以及用于工作区分析的正向运动学模型和逆向运动学模型的发展。介绍了从已开发的计算工具获得的初步结果。

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