A methodology of measuring coronary flow in a porcine aortic root using a pulsatile flow loop

机译：使用脉动流环测量猪主动脉根中冠状动脉血流的方法

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The purpose of the study is to develop an ex vivo testing methodology to quantify coronary artery flow using a pulsatile left heart simulator. A dissected porcine aorta was mounted on a Vivitro left heart simulator and its coronary artery flow was measured and calibrated to match previously recorded human coronary data^[1]. The method of aortic root attachment proved to fit the flow loop with no fluid leakage and the coronary flow conditions were found to match the baseline data trends with relatively good accuracy. This methodology may facilitate ex vivo measurement of coronary flow under various transcatheter valve deployment conditions.

机译：该研究的目的是开发一种体外测试方法，以使用搏动性左心模拟器对冠状动脉血流进行量化。将解剖的猪主动脉安装在Vivitro左心脏模拟器上，对其冠状动脉血流进行测量和校准，以匹配先前记录的人冠状动脉数据^{[1] 。经证实，主动脉根部附着方法可适应流环而无漏液，并且冠状动脉血流情况与基线数据趋势相匹配，具有相对较高的准确性。该方法可以促进在各种经导管瓣膜展开条件下的冠状动脉血的离体测量。}

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《Bioengineering Conference (NEBEC), 2012 38th Annual Northeast》|2012年|p.187- 188|共2页
会议地点 Philadelphia PA(US)
作者
Calderan Joe; Sirois Eric; Sun Wei;
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正文语种 eng
中图分类生物工程学（生物技术）;
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1. Optimal in vitro realization of pulsatile coronary artery flow waveforms using closed-loop feedback algorithms with multiple flow control devices [J] . SERDAR YILMAZ, ONUR TOKER, NURULLAH ARSLAN, Turkish Journal of Electrical Engineering and Computer Sciences . 2012,第6期

机译：使用带多个流量控制装置的闭环反馈算法，在体外实现脉搏性冠状动脉血流波形的最佳实现
2. Pulsatile flow studies of a porcine bioprosthetic aortic valve in vitro: PIV measurements and shear-induced blood damage. [J] . Lim WL, Chew YT, Chew TC, Journal of Biomechanics . 2001,第11期

机译：猪生物人工主动脉瓣的体外搏动流研究：PIV测量和剪切引起的血液损伤。
3. An Experimental Study of Pulsatile Flow in a Compliant Aortic Root Model under Varied Cardiac Outputs [J] . Ruihang Zhang, Yan Zhang Fluids . 2018,第4期

机译：不同心输出量的顺应性主动脉根模型脉动血流的实验研究
4. A methodology of measuring coronary flow in a porcine aortic root using a pulsatile flow loop [C] . Calderan Joe, Sirois Eric, Sun Wei Annual Northeast Bioengineering Conference . 2012

机译：使用脉动流量回路测量猪主动脉根中冠状动脉流动的方法
5. Systolic Coronary Flow Reversal and Abnormal Diastolic Flow Patterns in Patients With Aortic Stenosis : Assessment With an Intracoronary Doppler Catheter [D] . Yoshikawa, Junichi 1994

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A methodology of measuring coronary flow in a porcine aortic root using a pulsatile flow loop

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