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Noninvasive imaging of oral mucosae with optical coherence tomography

机译:光学相干层析成像技术对口腔黏膜的无创成像

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摘要

In this study, a swept-source optical coherence tomography (OCT) system is developed for in vivo visualization of structural and vascular morphology oral mucosa. For simplification of optical probe fabrication, probe weight, and system setup, the body of the scanning probe is fabricated by a 3D printer to fix the optical components and the mechanical scanning device, and a partially reflective slide is attached at the output end of probe to achieve a common-path configuration. Aside from providing the ability of 3D structural imaging with the developed system, 3D vascular images of oral mucosa can be simultaneously obtained. Then, different locations of oral mucosa are scanned with common-path OCT. The results show that epithelium and lamina propria layers as well as fungiform papilla can be identified and microvascular images can be acquired. With the proposed probe, the system cost and volume can be greatly reduced. Experimental results indicate that such common-path OCT system could be further implemented for oral cancer diagnosis.
机译:在这项研究中,扫描源光学相干断层扫描(OCT)系统被开发用于体内可视化口腔粘膜的结构和血管形态。为了简化光学探针的制造,探针的重量和系统设置,扫描探针的主体由3D打印机制造,以固定光学组件和机械扫描设备,并且在探针的输出端安装了部分反射的滑块。实现公共路径配置。除了使用开发的系统提供3D结构成像的功能外,还可以同时获得口腔粘膜的3D血管图像。然后,使用共通路径OCT扫描口腔粘膜的不同位置。结果表明,可以识别上皮和固有层以及真菌状乳头,并可以获取微血管图像。使用建议的探针,可以大大降低系统成本和体积。实验结果表明,这种共通OCT系统可以进一步用于口腔癌的诊断。

著录项

  • 来源
    《Biomedical imaging and sensing conference》|2017年|102511e.1-102511e.3|共3页
  • 会议地点 Yokohama(JP)
  • 作者单位

    Department of Electrical Engineering, Chang Gung University, Taoyuan, Taiwan;

    Department of Electrical Engineering, Chang Gung University, Taoyuan, Taiwan;

    Department of Electrical Engineering, Chang Gung University, Taoyuan, Taiwan,Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taiwan;

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  • 正文语种 eng
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