Abstract: We present an analytical perturbation analysis for studying the imaging characteristics of photon diffusion imaging in highly scattering media such as human tissues. The photon source, the optical properties of the sample, and measurement system are all considered as parts of the whole imaging system. A concise relation between the internal structure and the detected signal was derived. We also proved that photon diffusion imaging possess the property of linear shift invariance. The image formation mechanism of such measurements as functional imaging or tumor early diagnosis is illustrated from the point of linear shift invariant system view. !10
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