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首页> 外文会议>Conference on Optical Technologies in Biophysics and Medicine V and Saratov Fall Meeting; 20031007-20031010; Saratov; RU >New portable noninvasive spectrophotometric apparatus for clinical diagnostic applications
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New portable noninvasive spectrophotometric apparatus for clinical diagnostic applications

机译：用于临床诊断的新型便携式无创分光光度仪

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Today the noninvasive (in vivo, in situ) and real-time methods of diagnostics are desirable for general clinical practice. One of such promising technique is the optical multi-wave diffusion and absorption spectrophotometry. It allows a doctor to measure a number of important medical and biological (M&B) parameters such as the blood microcirculation parameters into the soft tissues, contents of the hemoglobin fractions into the periphery blood, etc. The use of the new components of the microelectronics and optics and development of new approaches to the diagnostic data processing makes it possible to design a of number of small and effective devices for this purpose. The basic principle of work of them in means of hardware function is the multi-wave light scanning of the tested tissue's area and detecting a backscattered light. In means of software function the basic principle of work of them is the inverse optical task solution when the optical and corresponding M&B parameters of the tested medium are calculated from the measured backscattered spectral optical data. This report presents one of such designed portable apparatus "Spectrotest"~R developed in cooperation with Moscow Regional Research and Clinical Institute of "MONIKI". This device allows a doctor to register the index of melanin pigmentation of the skin, the volume of the blood in the tested tissue and the average hemoglobin saturation of the peripheral blood. All this parameters are available for a doctor to see them on the monitor screen in real-time mode directly during any diagnostic or treatment procedure. For that a new modified light scattering theory with the analytical solution of the main equations has been developed. Analytical solution allows the software to calculate and indicate the measured M&B parameters on the computer's monitor screen during less than one second. Today the developed diagnostic system "Spectrotest"~R is used in real clinical practice in "MONIKI" and in the Oncology Center of the Russian Academy of Medical Science for the medical research aims. The general hardware and software composites of this diagnostic apparatus and examples of the application of it for the functional diagnostic tests are presented in this report as well.
机译：如今，非侵入性（体内，原位）诊断和实时诊断方法是一般临床实践所需要的。这种有前途的技术之一是光学多波扩散和吸收分光光度法。它使医生能够测量许多重要的医学和生物学（M＆B）参数，例如进入软组织的血液微循环参数，进入外周血的血红蛋白部分的含量等。使用微电子学的新组件和光学技术和诊断数据处理新方法的发展使得有可能为此目的设计许多小型而有效的设备。它们在硬件功能上的基本工作原理是对被测组织的区域进行多波光扫描并检测反向散射光。在软件功能方面，它们的基本工作原理是反光学任务解决方案，即根据测得的反向散射光谱光学数据计算出被测介质的光学和相应的M＆B参数。本报告介绍了与莫斯科地区研究与临床研究所“ MONIKI”合作开发的一种此类便携式设备“ Spectrotest”〜R。该设备允许医生记录皮肤黑色素的色素沉着指数，被测组织中的血液量以及外周血的平均血红蛋白饱和度。所有这些参数可供医生在任何诊断或治疗过程中直接在实时模式下的监视器屏幕上查看。为此，已经开发了一种具有主要方程的解析解的新的改进的光散射理论。分析解决方案使软件可以在不到一秒钟的时间内计算并在计算机的监视器屏幕上显示测得的M＆B参数。如今，已开发的诊断系统“ Spectrotest”〜R已在“ MONIKI”和俄罗斯医学科学院肿瘤学中心的实际临床实践中用于医学研究。此报告还介绍了此诊断设备的一般硬件和软件组合以及其在功能诊断测试中的应用示例。

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