首页> 外文会议>Conference on Optical Technologies in Biophysics and Medicine V and Saratov Fall Meeting; 20031007-20031010; Saratov; RU >Influence of low level laser irradiation to phagocytosis activity and proinflammation cytokins production
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Influence of low level laser irradiation to phagocytosis activity and proinflammation cytokins production

机译:低水平激光照射对吞噬活性和神经炎症细胞因子产生的影响

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In this work was studied the influence of low-level laser irradiation (LLLI) generating semiconductor devices in red (650 nm) and infrared (850 nm) ranges of wavelength, in condition in vitro and in vivo on phagocytosis activity and synthesis by peritoneal macrophages endogenic proinflammatory cytokins at phagocytosis bacterial cells. In the power of phagocytosis stage was used the culture of clinical strains of enteropathogenic Escherichia coli. The variation of dose rendering influence accomplished with the help of variation power and an exposition of irradiation. Receiving results are evidence of stimulating activity infrared LLLI on phagocytosis activity of macrophages. We revealed the intensification of adhesion bacteria by macrophages, the intensification of bacteria's killing, and increase of production proinflammatory cytokins. Moreover we described effective revealed dose-dependent character. Influence of rays a red region of spectrum on phagocytosis macrophages caused some reduction of their activity increasing radiation dose was marked the destruction of the most macrophages.
机译:在这项工作中,研究了在体外和体内条件下,在红色(650 nm)和红外(850 nm)波长范围内产生低水平激光辐射(LLLI)的半导体器件对吞噬活性和腹膜巨噬细胞合成的影响吞噬作用细菌细胞中的内源性促炎细胞因子。在吞噬作用阶段中,使用了肠病原性大肠杆菌临床菌株的培养。剂量变化影响的变化借助于变化功率和辐照的曝光而完成。接收结果是刺激红外LLLI对巨噬细胞吞噬活性的活性的证据。我们揭示了巨噬细胞对粘附细菌的强化作用,对细菌的杀伤作用的强化作用以及促炎性细胞因子产生的增加。此外,我们描述了有效的揭示剂量依赖性特征。射线的红色光谱区域对吞噬作用巨噬细胞的影响导致其活性降低,辐射剂量增加,标志着大多数巨噬细胞的破坏。

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