Label-free detection of cytokines using optical microcavities

机译：使用光学微腔无标记检测细胞因子

获取原文

获取原文并翻译 | 示例

页面导航

摘要
著录项
相似文献
相关主题

摘要

Ultra-high-Q microresonators have demonstrated sensitive and specific chemical and biological detection. The sensitivity is derived from the long photon lifetime inside the cavity and specificity is achieved through surface functionalization. Here, ultra-high-Q microcavities demonstrate label-free, single molecule detection of Interleukin-2 (IL-2) in fetal bovine serum (FBS). IL-2 is a cytokine released in response to immune system activation. The surface of the microtoroids was sensitized using anti-IL-2. The detection mechanism relies upon a thermo-optic mechanism to enhance resonant wavelength shifts induced through binding of a molecule.

机译：超高Q微谐振器已证明灵敏且特异的化学和生物检测。灵敏度源自腔体内的长光子寿命，并且通过表面功能化实现了特异性。在这里，超高Q微腔展示了胎牛血清（FBS）中白细胞介素2（IL-2）的无标记单分子检测。 IL-2是响应免疫系统激活而释放的细胞因子。使用抗IL-2使微环的表面敏化。该检测机制依赖于热光机制来增强通过分子结合引起的共振波长偏移。

著录项

来源
《Conference on Single Molecule Spectroscopy and Imaging; 20080119-21; San Jose,CA(US)》|2008年|P.ixi|共2页
会议地点 San JoseCA(US)
作者
Andrea M. Armani; Scott E. Fraser;
展开▼
作者单位

Department of Applied Physics, California Institute of Technology 1200 E California Blvd, Pasadena, CA 91125;

Division of Biology, California Institute of Technology 1200 E California Blvd, Pasadena, CA 91125;

展开▼
会议组织
原文格式 PDF
正文语种 eng
中图分类医用物理学;
关键词

相似文献

外文文献
中文文献
专利

1. A SIMULTANEOUS MULTI-PROBE DETECTION LABEL-FREE OPTICAL-RESOLUTION PHOTOACOUSTIC MICROSCOPY TECHNIQUE BASED ON MICROCAVITY TRANSDUCER [J] . WU LIRU, CHI YAN, WU YONGBO, Journal of innovative optical health sciences . 2013,第03期

机译：基于微腔换能器的多探针同时检测无标签光声显微技术
2. Label-Free, Single-Molecule Detection with Optical Microcavities [J] . Andrea M. Armani, Rajan P. Kulkarni, Scott E. Fraser, Science . 2007,第5839期

机译：带有光学微腔的无标签单分子检测
3. Label-Free Pb(II) Whispering Gallery Mode Sensing Using Self- Assembled Glutathione-Modified Gold Nanoparticles on an Optical Microcavity [J] . Sirirat Panich, Kerry A. Wilson, Philippa Nuttall, Analytical chemistry . 2014,第13期

机译：使用自组装的谷胱甘肽修饰的金纳米粒子在光学微腔上的无标签Pb（II）耳语画廊模式感测。
4. Label-free detection of cytokines using optical microcavities [C] . Andrea M. Armani, Scott E. Fraser Conference on Single Molecule Spectroscopy and Imaging . 2008

机译：使用光学微腔免费无标记检测细胞因子
5. Label-Free Biosensors for Cytokine Detection. [D] . Oh, Bo-Ram. 2016

机译：用于细胞因子检测的无标记生物传感器。
6. Ultraspecific and Highly Sensitive Nucleic Acid Detection by Integrating a DNA Catalytic Network with a Label-Free Microcavity [O] . Dr. Yuqiang Wu, Dr. David Yu Zhang, Dr. Peng Yin, -1

机译：通过将DNA催化网络与无标记微腔相集成来进行超特异性和高灵敏度的核酸检测
7. Label-free detection of cytokines using optical microcavities [O] . Andrea M. Armani, Scott E. Fraser 2008

机译：使用光学微腔免费无标记检测细胞因子

Label-free detection of cytokines using optical microcavities

摘要

著录项

相似文献

相关主题

期刊订阅