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首页> 外文会议>Digital mammography >A Comparative Study of Volumetric and Area-Based Breast Density Estimation in Digital Mammography: Results from a Screening Population
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A Comparative Study of Volumetric and Area-Based Breast Density Estimation in Digital Mammography: Results from a Screening Population

机译：乳腺X线摄影中基于体积和面积的乳房密度估计的比较研究：筛查人群的结果

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摘要

We compare a volumetric versus an area-based breast density estimation method in digital mammography. Bilateral images from 71 asymptomatic women were analyzed. Volumetric density was measured using Quantra? (Hologic Inc.). Area-based density was estimated using Cumulus (Ver. 4.0, Univ. Toronto). Correlation and regression analysis was performed to determine the association between ;') density from left versus right breasts and ii) volumetric versus the area-based measures. Volumetric breast density measures are strongly correlated but statistically significantly different than the area-based measures (r=0.79, p<0.001). Regression demonstrates a significant non-linear association (R~2=0.70, p<0.001). The density correlation between right and left breasts is also strong for both methods, (r>0.95, p<0.001). The strong association with the area-based density measures suggests that volumetric breast density could potentially also aid in breast cancer risk estimation. The observed non-linear association between volumetric and area-based estimates may have implications for risk stratification in clinical practice.
机译：我们在数字乳腺X线摄影术中比较了容积式和基于区域的乳房密度估计方法。分析了来自71名无症状女性的双边图像。体积密度使用Quantra？ （Hologic Inc.）。使用Cumulus（4.0版，多伦多大学）估算基于面积的密度。进行了相关和回归分析，以确定;'）左右乳房的密度与ii）体积与基于面积的测量之间的关联。乳房体积密度测量值与基于面积的测量值高度相关，但在统计学上有显着差异（r = 0.79，p <0.001）。回归显示出显着的非线性关联（R〜2 = 0.70，p <0.001）。两种方法左右乳房之间的密度相关性也很强（r> 0.95，p <0.001）。与基于面积的密度测量值的紧密关联表明，乳房体积密度还可能有助于乳腺癌风险评估。在体积和基于面积的估计值之间观察到的非线性关联可能对临床实践中的风险分层有影响。

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  • 来源
    《Digital mammography》|2010年|p.378-385|共8页
  • 会议地点 Girona(ES);Girona(ES)
  • 作者

    Despina Kontos; Predrag R. Bakic; Raymond J. Acciavatti; Emily F. Conant; Andrew D.A. Maidment;

  • 作者单位

    Department of Radiology, University of Pennsylvania, 1 Silverstein Building HUP, 3400 Spruce Street, Philadelphia, PA 19104-4206;

    Department of Radiology, University of Pennsylvania, 1 Silverstein Building HUP, 3400 Spruce Street, Philadelphia, PA 19104-4206;

    Department of Radiology, University of Pennsylvania, 1 Silverstein Building HUP, 3400 Spruce Street, Philadelphia, PA 19104-4206;

    Department of Radiology, University of Pennsylvania, 1 Silverstein Building HUP, 3400 Spruce Street, Philadelphia, PA 19104-4206;

    Department of Radiology, University of Pennsylvania, 1 Silverstein Building HUP, 3400 Spruce Street, Philadelphia, PA 19104-4206;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物医学工程;
  • 关键词

    volumetric breast density; digital mammography; breast cancer risk;

    机译：乳房容积数字乳腺摄影乳腺癌风险;

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